4-[4-(4-methyl-2-methylamino-thiazol-5-yl)-pyrimidin-2-ylamino]-phenol

This compound is a synthetic small molecule belonging to the class of trisubstituted thiazoles. It has the molecular formula C15H15N5OS and a molecular weight of approximately 313.38 g/mol. The structure features a phenolic group linked via an amino bridge to a pyrimidine ring, which is further substituted with a methyl-substituted thiazole moiety. It is catalogued as DrugBank DB04407 and ChEBI:41583. The compound has been studied experimentally but has not been approved for any therapeutic use or entered clinical trials beyond preclinical/experimental stages. Its primary known biological interaction is ATP binding, with potential relevance to cyclin-dependent kinase (CDK) pathways—specifically CDK2—suggesting possible antiproliferative activity; however, no detailed mechanism of action or clinical indication has been established[1][8][9].

Other names

4-[4-(4-METHYL-2-METHYLAMINO-THIAZOL-5-YL)-PYRIMIDIN-2-YLAMINO]-PHENOL4-{4-[4-methyl-2-(methylamino)-1,3-thiazol–5–yl]–2-pyrimidinyl}aminophenolPhenol, 4-[[4-[4-methyl–2-(methylamino)–5-thiazolyl]–2-pyrimidinyl]amino]